E-ISSN 2367-699X | ISSN 2367-7414
 
2021, Vol: 7, Issue: 3
7/3Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles
Required files to be uploaded

Copyright Transfer Form

Case Report 


UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka.

Cited by (1)

Abstract
GIST tumors is very unusual in the young and middle aged and a high index of suspicion is needed for the diagnosis in young patients who present with upper gastrointestinal bleeding. Appropriate imaging such as a Computed tomographic scan (CT scan) may identify this tumor which may easily be misdiagnosed as a bleeding Peptic Ulcer Disease in the young.
We present a case of a healthy 38 year old man with no alcohol use who presented with epigastric pain and melena and subsequent torrential bleeding uncontrolled during endoscopy necessitating an emergency exploratory laparotomy by the general surgery team. The bleeding intraluminal component of the tumor with gross splenic and pancreatic involvement was identified and surgical management consisted of a wedge resection of the greater curvature of the stomach incorporating the tumor and the spleen with successful dissection of the tumor off the tail of the pancreas. Histology was positive for C-KIT and DOG-1 markers. Postoperative course was uneventful and he is presently on Imatinib Mesylate.

Key words: Gastrointestinal stromal tumor; endoscopy; C-KIT, DOG-1


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ayodele Atolagbe
Articles by Rahaman Oloruntobi
Articles by Ogunleye Adeyemi
Articles by Apakama Chukwuemeka
on Google
on Google Scholar


REFERENCES
1. Shahnazarian V, Fazio L: Gastrointestinal stromal tumor (GIST) in a young man with unprovoked hematemesis BMJ Case Rep. 2013 [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
2. Beham AW, Schaefer I, Schuler P, et al. Gastrointestinal stromal tumors. Int J Colorectal Dis2012; 27: 689-700 [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
3. Miettinen M, Lasota J. Gastrointestinal stromal tumors: pathology and prognosis at different sites Semin Diagn Pathol 2006 23:70 [DOI via Crossref]    [Pubmed]   
4. Zhao X, Yue C: Gastrointestinal stromal tumor. J of Gastrointestinal Oncology 2012; 3:189-208 [Pubmed]    [PMC Free Fulltext]   
5. Roggin K, Posner M: Modern treatment of gastric gastrointestinal stromal tumors. World J of Gastroenterology 2012 Dec14; 18(46):6720-28. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
6. Miettinen M, Wang Z, Lasota J DOG 1 antibody in the differential diagnosis of gastrointestinal stromal tumors: a study of 1840 cases Am J Surg Pathol 2009 Sep; 33(9): 1401-8 [DOI via Crossref]    [Pubmed]   
7. Miettinen M, Lasota J: Review Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med. 2006 Oct; 130(10):1466-78. [Pubmed]   
8. Miettinen M, Lasota J, Sobin LH: Gastrointestinal stromal tumors of the stomach in children and young adults: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with long-term follow-up and review of the literature. Am J Surg Pathol 29(10):1373-81 [DOI via Crossref]    [Pubmed]   
9. Scarpa M, Bertin M, Ruffolo C, Polese L, et al. A systematic review on the clinical diagnosis of gastrointestinal stromal tumors. J Surg Oncol. 2008;98(5):384. [DOI via Crossref]    [Pubmed]   
10. Janeway KA, Pappo A. Treatment guidelines for gastrointestinal stromal tumors in children and young adults. J Pediatr Hematol Oncol. 2012 may;34 69-72 [DOI via Crossref]    [Pubmed]   
11. Dematteo RP, Gold JS, Saran L, Gonen M et al. Tumor mitotic rate, size, and location independently predict recurrence after resection of Gastrointestinal stromal tumor (GIST) Cancer 2008 Feb 1; 112(3): 608-15 [DOI via Crossref]    [Pubmed]   
12. Miettinen M, Sobin LH, Lasota J Gastrointestinal stromal tumors of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am J Surg Pathol. 2005; 29(1):52. [DOI via Crossref]    [Pubmed]   
13. Aomatsu N, Nakamura M, Takeuchi K, Nishii T, et al.: A case of emergency resection of a giant gastrointestinal stromal tumor of the stomach associated with hemorrhagic shock Gan To Kagaku Ryoho. 2013 Nov;40 (12):2185-87 [Pubmed]   
14. Seya T, Tanaka N, Yokoi K, Shinji S, et al. Life-threatening bleeding from Gastrointestinal stromal tumor of the stomach J Nippon Medical School 2008 Oct; 75(5):306-11 [DOI via Crossref]    [Pubmed]   
15. Fletcher C, Berman J, Corless C, et al. Diagnosis of Gastrointestinal stromal tumors: a consensus approach Int J Surg Path 2002;10:81
16. Oladeji O, Wardelmann E, Ronellenfitsch U, Pink D, et al. Pattern of recurrence in patients with ruptured primary gastrointestinal tumor (GIST) J clinical oncology vol 28 2010:10053
17. DeMatteo RP, Lewis JJ, Leung D, et al. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg 2000; 231:51-8 [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   

This Article Cited By the following articles

Gastrointestinal Stromal Tumor of the Jejunum With Active Bleeding Demonstrated on Dual-Energy MDCT Angiography: A Case Report
Current Problems in Diagnostic Radiology 2019; 48(3): 298.

1
 
How to Cite this Article
Pubmed Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka. UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?. Int J Surg Med. 2015; 1(2): 72-75. doi:10.5455/ijsm.20150917100638

Web Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka. UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?. http://www.ejos.org/?mno=201307 [Access: November 03, 2020]. doi:10.5455/ijsm.20150917100638

AMA (American Medical Association) Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka. UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?. Int J Surg Med. 2015; 1(2): 72-75. doi:10.5455/ijsm.20150917100638


Vancouver/ICMJE Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka. UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?. Int J Surg Med. (2015), [cited November 03, 2020]; 1(2): 72-75. doi:10.5455/ijsm.20150917100638


Harvard Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka (2015) UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?. Int J Surg Med, 1 (2), 72-75. doi:10.5455/ijsm.20150917100638


Turabian Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka. 2015. UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?. International Journal of Surgery and Medicine, 1 (2), 72-75. doi:10.5455/ijsm.20150917100638


Chicago Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka. "UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?." International Journal of Surgery and Medicine 1 (2015), 72-75. doi:10.5455/ijsm.20150917100638


MLA (The Modern Language Association) Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka. "UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?." International Journal of Surgery and Medicine 1.2 (2015), 72-75. Print. doi:10.5455/ijsm.20150917100638


APA (American Psychological Association) Style

Ayodele Atolagbe, Rahaman Oloruntobi, Ogunleye Adeyemi, Apakama Chukwuemeka (2015) UPPER GASTRO-INTESTINAL BLEEDING IN THE YOUNG - GASTRIC GIST TUMOR OR PEPTIC ULCER DISEASE?. International Journal of Surgery and Medicine, 1 (2), 72-75. doi:10.5455/ijsm.20150917100638


Author Login Reviewer Login About Publisher Editorial Policies Peer Review Policy Editorial & Peer Review Process Author's Rights and Obligations Publication Ethics and Publication Malpractice Statement Conflict of Interest Policy Plagiarism Policy Protection of Research Participants (Statement On Human And Animal Rights) Privacy Policy Publication Ethics and Publication Malpractice Statement Corrections, Retractions & Expressions of Concern Self-Archiving Policies Statement of Informed Consent Advertising Policy Terms of Use License Information
Copyright © 2021 International Journal of Surgery and Medicine All Rights Reserved. Subject to change without notice from or liability to International Journal of Surgery and Medicine.
For best results, please use Internet Explorer or Google Chrome

Contact Information


 

Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the International Journal of Medical Reviews and Case Reports editorial office as follows:

Bulgarian Association of Young Surgeons (BAYS);

National Center of Public Health and Analyses (NCPHA), floor 2, office № 31,  Sofia 1431, Bulgaria.

inkov@journalmedica.com

Financial department is managed by International Sci Ink Press. 

It is a company registered in Bulgaria with registered no. 205414288 and registered address at 57 Antim I str., Vazrazhdane, Sofia, 1303, Bulgaria.