E-ISSN 2367-699X | ISSN 2367-7414
 

Short Communication

Online Publishing Date:
29 / 05 / 2016

 


ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS

Amel Harzallah, Hayet Kaaroud, Hamida Bezzine, Fethi Ben Hamida, Taieb Ben Abdallah.


Cited By: 2

Abstract
Endocarditis is one of the most prevalent forms of cardiac involvement in patients with lupus, as it is considered as one a life-threatening complication. Libman-Sacks endocarditis is common. Infective endocarditis can also cause complications within immunocompromised patients.
The aim of this study is to determine particularities of endocarditis in patients with lupus and to look for distinguishing features between infectious or immunological origin. A retrospective study was conducted on patients with lupus presenting endocarditis. Lupus was diagnosed according to the American college of rheumatology criteria. The diagnosis of endocarditis was made based on the modified Duke criteria.
The present case report studies seven cases of endocarditis. Six of these patients are women and the other one is a man. They are aged meanly of 29.4 years (extremes: 20-36). Fever was present in all the cases with a new cardiac murmur in six cases and a modification of its intensity in one case. Biologic inflammatory syndrome was present in six cases. Cardiac ultrasound performed in six cases made the diagnosis of endocarditis which involved the left heart valves in five cases and the right heart valves in one case. Valvular insufficiency was identified in six patients. The valve involvement was mitral in two cases, mitro-aortic in two others, aortic in the fifth one and tricuspid in the sixth one. Endocarditis was infectious in 4 cases, thanks to positive blood culture. The germs identified were gram negative bacilli in two cases, anaerobic organism in one case and gram positive cocci in one case. Candida albicans was isolated in one case. Libman-Sacks endocarditis was objectified in three cases. A combination of Libman-Sacks endocarditis with infectious endocarditis was diagnosed in one case. The treatment consisted of antibiotics in four cases with surgery in two cases. The outcome was favorable in five cases and fatal in the two others.
Endocarditis in lupus can be infectious or Libman-Sacks endocarditis. These two conditions share several clinical features. The only distinctive argument remains positive blood culture. The treatment should be initiated as early as possible to limit the valve damage and improve the outcome.

Key words: Systemic lupus erythematosus, infectious endocarditis, Libman-Sacks endocarditis


 
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This Article Cited By the following articles

A Review of Cardiac Manifestations in Patients With Systemic Lupus Erythematosus and Antiphospholipid Syndrome With Focus on Endocarditis
2022; (): .

1
 
Occult Presentation of Infective Endocarditis in Systemic Lupus Erythematosus
2022; 41(11): e500.

2
 
How to Cite this Article
Pubmed Style

Harzallah A, Kaaroud H, Bezzine H, Hamida FB, Abdallah TB. ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS. Int J Surg Med. 2018; 4(3): 158-163. doi:10.5455/ijsm.endocarditis


Web Style

Harzallah A, Kaaroud H, Bezzine H, Hamida FB, Abdallah TB. ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS. https://www.ejos.org/?mno=216013 [Access: February 19, 2024]. doi:10.5455/ijsm.endocarditis


AMA (American Medical Association) Style

Harzallah A, Kaaroud H, Bezzine H, Hamida FB, Abdallah TB. ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS. Int J Surg Med. 2018; 4(3): 158-163. doi:10.5455/ijsm.endocarditis



Vancouver/ICMJE Style

Harzallah A, Kaaroud H, Bezzine H, Hamida FB, Abdallah TB. ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS. Int J Surg Med. (2018), [cited February 19, 2024]; 4(3): 158-163. doi:10.5455/ijsm.endocarditis



Harvard Style

Harzallah, A., Kaaroud, . H., Bezzine, . H., Hamida, . F. B. & Abdallah, . T. B. (2018) ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS. Int J Surg Med, 4 (3), 158-163. doi:10.5455/ijsm.endocarditis



Turabian Style

Harzallah, Amel, Hayet Kaaroud, Hamida Bezzine, Fethi Ben Hamida, and Taieb Ben Abdallah. 2018. ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS. International Journal of Surgery and Medicine, 4 (3), 158-163. doi:10.5455/ijsm.endocarditis



Chicago Style

Harzallah, Amel, Hayet Kaaroud, Hamida Bezzine, Fethi Ben Hamida, and Taieb Ben Abdallah. "ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS." International Journal of Surgery and Medicine 4 (2018), 158-163. doi:10.5455/ijsm.endocarditis



MLA (The Modern Language Association) Style

Harzallah, Amel, Hayet Kaaroud, Hamida Bezzine, Fethi Ben Hamida, and Taieb Ben Abdallah. "ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS." International Journal of Surgery and Medicine 4.3 (2018), 158-163. Print. doi:10.5455/ijsm.endocarditis



APA (American Psychological Association) Style

Harzallah, A., Kaaroud, . H., Bezzine, . H., Hamida, . F. B. & Abdallah, . T. B. (2018) ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS. International Journal of Surgery and Medicine, 4 (3), 158-163. doi:10.5455/ijsm.endocarditis