E-ISSN 2367-699X | ISSN 2367-7414
 
2023, Vol: 9, Issue: 5
9 / 5Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Copyright Transfer Form

Case Report

Online Publishing Date:
24 / 09 / 2017

 


SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov.


Abstract
Purpose: Small cell neuroendocrine bladder carcinoma is a rare entity, account for less than 1% of all bladder tumors. They are of particular histological entity characterized by an aggressive clinical behaviour, high potential for metastatic spread and poor prognosis. The aim of this study was to describe the epidemiological, clinical, therapeutic modalities and the evolution data of small cell neuroendocrine bladder carcinomas.
Patients and methods: During a period of 10 years, four patients with neuroendocrine bladder carcinoma were treated at the National Institute of Oncology in Rabat.
Results: The median age was 66 years. There were three men and a woman. Neuroendocrine carcinoma was pure in one case and associated with transitional cell carcinoma in the other three cases. Two patients were diagnosed with lymph nodes involvement and one patient at a metastatic stage. A cystectomy was performed in one case. Two patients received a concurrent chemoradiation and the fourth patient received chemotherapy alone. A single case of complete remission was observed. Median survival was 18 months (6–30 months). Only one patient is still alive 30 months after diagnosis.
Conclusion: The management of neuroendocrine carcinoma of the bladder remains debated and vary from institution to author. Despite multimodality regimens, the prognosis of these tumours remains poor.

Key words: Small cell carcinoma, bladder, diagnosis, radiotherapy, chemotherapy, surgery


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Imane Bourhafour
Articles by Sanaa Elmajjaoui
Articles by Hanane Elkacemi
Articles by Tayeb Kebdani
Articles by Noureddine Benjaafar
Articles by Mila Kayryakova
Articles by Ivan Inkov
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov. SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE. Int J Surg Med. 2018; 4(2): 96-100. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management

Web Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov. SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE. https://www.ejos.org/?mno=234988 [Access: February 20, 2024]. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management

AMA (American Medical Association) Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov. SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE. Int J Surg Med. 2018; 4(2): 96-100. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management


Vancouver/ICMJE Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov. SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE. Int J Surg Med. (2018), [cited February 20, 2024]; 4(2): 96-100. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management


Harvard Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov (2018) SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE. Int J Surg Med, 4 (2), 96-100. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management


Turabian Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov. 2018. SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE. International Journal of Surgery and Medicine, 4 (2), 96-100. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management


Chicago Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov. "SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE." International Journal of Surgery and Medicine 4 (2018), 96-100. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management


MLA (The Modern Language Association) Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov. "SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE." International Journal of Surgery and Medicine 4.2 (2018), 96-100. Print. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management


APA (American Psychological Association) Style

Imane Bourhafour, Sanaa Elmajjaoui, Hanane Elkacemi, Tayeb Kebdani, Noureddine Benjaafar, Mila Kayryakova, Ivan Inkov (2018) SMALL CELL NEUROENDOCRINE CARCINOMA OF THE BLADDER: REPORT OF FOUR CASES AND A REVIEW OF THE LITERATURE. International Journal of Surgery and Medicine, 4 (2), 96-100. doi:10.5455/ijsm.small-cell-neuroendocrine-carcinoma-management


Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information

About International Journal of Surgery and Medicine

International Journal of Surgery and Medicine E-ISSN: 2367-699X | P-ISSN: 2367-7414 International Journal of Surgery and Medicine (IJSM) is an inter ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information


 

Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the International Journal of Surgery and Medicine editorial office as follows:

Bulgarian Association of Young Surgeons (BAYS)

inkov@journalmedica.com

Financial department is managed by International Sci Ink Press. 

It is a company registered in Bulgaria with registered no. 205414288 and registered address at 57 Antim I str., Vazrazhdane, Sofia, 1303, Bulgaria.

Tel: +359883427500