E-ISSN 2367-699X | ISSN 2367-7414
 

Review Article 


Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials

Zackariah Clement.

Abstract
Background
Breast conserving surgery (BCS) is the standard of care for women with early breast cancer. The margin status is crucial in breast conserving surgery and is an important determinant for local recurrence. Local recurrence is associated with decreased overall and disease-free survival. Several studies have shown that cavity shave margin reduces the rate of positive margins and local recurrence. This review analyses the randomised controlled trials to compare the role of cavity shave margin in breast conserving surgery and its effect on positive margins and re-excision rates.
Methods
A systematic search of literature published before December 2016 for randomised controlled trials in MEDLINE, Pubmed, EMBASE, Proquest, Cochrane central register of controlled trials and Google scholar was peformed. Out of 12 articles 2 randomised controlled trials were eligible. Positive margins and re-excision rates were analysed using odds ratio and risk difference.
Results
Out of 12 studies, 2 were suitable for review. Overall positive margins were 18.3% and 36% in the CSM and No-CSM groups respectively, with an odds ratio of 0.373 (95% CI, 0.189 to 0.739, P = 0.232) and risk difference of -0.194 (95% CI, -0.336 to -0.053, P= 0.198). The re-excision rates were lower in the CSM group when compared to the No-CSM group (12.2% vs 31.3%) with an odds ratio of 0.28 (95% CI, 0.160 to 0.520, P=0.578) and risk difference was -0.199 (95% CI, -0.309 to -0.089, P=0.264).
Conclusion
Analysis of the randomised controlled trials showed that cavity shave margins significantly reduced the risk of positive margins and the need for re-excision. It is a beneficial technique in women undergoing lumpectomy and breast conserving surgery.
Keywords: Early breast cancer, breast conserving surgery, cavity shave margins.

Key words: Early breast cancer, breast conserving surgery, cavity shave margins.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Zackariah Clement
on Google
on Google Scholar
Article Statistics
 Viewed: 2275
Downloaded: 472
Cited: 0

How to Cite this Article
Pubmed Style

Zackariah Clement. Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials. Int J Surg Med. 2017; 3(3): 177-182. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery


Web Style

Zackariah Clement. Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials. http://www.ejos.org/?mno=262107 [Access: April 26, 2019]. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery


AMA (American Medical Association) Style

Zackariah Clement. Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials. Int J Surg Med. 2017; 3(3): 177-182. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery



Vancouver/ICMJE Style

Zackariah Clement. Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials. Int J Surg Med. (2017), [cited April 26, 2019]; 3(3): 177-182. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery



Harvard Style

Zackariah Clement (2017) Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials. Int J Surg Med, 3 (3), 177-182. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery



Turabian Style

Zackariah Clement. 2017. Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials. International Journal of Surgery and Medicine, 3 (3), 177-182. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery



Chicago Style

Zackariah Clement. "Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials." International Journal of Surgery and Medicine 3 (2017), 177-182. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery



MLA (The Modern Language Association) Style

Zackariah Clement. "Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials." International Journal of Surgery and Medicine 3.3 (2017), 177-182. Print. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery



APA (American Psychological Association) Style

Zackariah Clement (2017) Should cavity shave margins be performed as a routine in breast conserving surgery? A review of randomised controlled trials. International Journal of Surgery and Medicine, 3 (3), 177-182. doi:10.5455/ijsm.cavity-shave-margin-breast-conserving-surgery