E-ISSN 2367-699X | ISSN 2367-7414
 

Case Report 


Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.

Aun Jamal, Zahra Jahangir, Tabish Saleem, Jibran Mohsin , Ihtisham ul Haq, Faizan Ullah, osama shakeel, Hassaan Bari, Aamir Ali Syed, Shahid Khattak, Faisal Hanif.

Abstract
Introduction
Necrolytic migratory erythema (NME) is a disorder that is recognized by reddish, migrating areas of blistering that heal with pigmentation. It is a characteristic rash that is often recognized by its distinct appearance and history. It has strong association with glucagonoma, a pancreatic neuroendocrine tumor arising from the alpha type islet cells. In such cases NME presents as a paraneoplastic manifestation of the disease. The diagnosis of this rare tumor depends on high index of suspicion on the basis of history and examination and relevant pathological and radiological investigations. This tumor is potentially curable by surgery.
Case Presentation
In this article the authors describe a 36 years old female patient with NME and a multifocal pancreatic neuroendocrine tumor with clinical features of glucagonoma syndrome. After investigations she underwent total pancreatectomy and within a few days her skin lesions and clinical symptoms started improving.
Conclusion
Prompt diagnosis and management are of paramount importance in the management of glucagonoma. It is possible if there is high index of suspicion and the management is done appropriately.

Key words: Necrolytic migratory erythema, glucagonoma, neuroendocrine tumor, blistering skin rash


 
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How to Cite this Article
Pubmed Style

Jamal A, Jahangir Z, Saleem T, JM, Haq Iu, Ullah F, shakeel o, Bari H, Syed AA, Khattak S, Hanif F, . Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.. doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020


Web Style

Jamal A, Jahangir Z, Saleem T, JM, Haq Iu, Ullah F, shakeel o, Bari H, Syed AA, Khattak S, Hanif F, . Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.. http://www.ejos.org/?mno=302645291 [Access: November 03, 2020]. doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020


AMA (American Medical Association) Style

Jamal A, Jahangir Z, Saleem T, JM, Haq Iu, Ullah F, shakeel o, Bari H, Syed AA, Khattak S, Hanif F, . Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.. doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020



Vancouver/ICMJE Style

Jamal A, Jahangir Z, Saleem T, JM, Haq Iu, Ullah F, shakeel o, Bari H, Syed AA, Khattak S, Hanif F, . Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.. doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020



Harvard Style

Jamal, A., Jahangir, Z., Saleem, T., , J. M., Haq, I. u., Ullah, F., shakeel, o., Bari, H., Syed, A. A., Khattak, S., Hanif, F. & (2020) Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.. doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020



Turabian Style

Jamal, Aun, Zahra Jahangir, Tabish Saleem, Jibran Mohsin, Ihtisham ul Haq, Faizan Ullah, osama shakeel, Hassaan Bari, Aamir Ali Syed, Shahid Khattak, Faisal Hanif, and . 2020. Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.. doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020



Chicago Style

Jamal, Aun, Zahra Jahangir, Tabish Saleem, Jibran Mohsin, Ihtisham ul Haq, Faizan Ullah, osama shakeel, Hassaan Bari, Aamir Ali Syed, Shahid Khattak, Faisal Hanif, and . "Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.." doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020



MLA (The Modern Language Association) Style

Jamal, Aun, Zahra Jahangir, Tabish Saleem, Jibran Mohsin, Ihtisham ul Haq, Faizan Ullah, osama shakeel, Hassaan Bari, Aamir Ali Syed, Shahid Khattak, Faisal Hanif, and . "Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.." doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020



APA (American Psychological Association) Style

Jamal, A., Jahangir, Z., Saleem, T., , J. M., Haq, I. u., Ullah, F., shakeel, o., Bari, H., Syed, A. A., Khattak, S., Hanif, F. & (2020) Solving up the jigsaw puzzle: Necrolytic Migratory Erythema Associated with Multifocal Neuroendocrine Tumor of Pancreas, A case report.. doi:10.5455/ijsm.Neuroendocrine-Tumor-Pancreas-case-report-06-2020