E-ISSN 2367-699X | ISSN 2367-7414
 

Case Report 


Multimodal approach for metastatic colorectal cancer – a clinical model: Case report

Tsvetelina Paycheva , Kostadin Angelov , Vasil Pavlov, Svilen Maslyankov.

Abstract
Background: Colorectal cancer is a socially significant disease because of its high morbidity and mortality rates. It requires integrated work of many medical specialist in order to achieve better treatment results and better quality of life to those patients. The presented case illustrates our clinical model for multidisciplinary approach.
Case summary: The presented case is about 74 years old patient with metastatic colorectal cancer. He underwent resection of the sigmoid colon. Later on was discovered a single metastatic lesion in the left lung and lower left lobectomy was performed. Couple of mounts later he was readmitted to Surgery Clinic with abdominal pain and discomfort due to new liver lesion. He underwent liver resection and started first line chemotherapy on FOLFOX-6 scheme. On next clinical reevaluation it appeared to be ineffective. The disease disseminated in liver, visceral peritoneum, spinal and pelvic bones. Second line chemotherapy with FOLFIRI scheme couldn’t stop further progression and palliative radiotherapy was scheduled in order to manage the pain syndrome. Afterwards he underwent spinal surgery, because of pathologic fracture of L5 and started third line Capecitabine as monotherapy.
Conclusions: Multidisciplinary approach is the only relevant treatment option for patients with metastatic colorectal cancer. This case demonstrates the advantages in terms of overall survival and progression free survival, in the context of late diagnosis and comorbid terrain. It also raises questions to the findings in patients with progression and chemo-resistance in colorectal tumors, published by leading world cancer centers.

Key words: CRC, colorectal cancer, sigmoid cancer, multimodal approach, Chemotherapy, FOLFOX-6, FOLFIRI, Capecitabine, Metastasis, PET/CT, Radiotherapy, progression


 
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How to Cite this Article
Pubmed Style

TP, KA, Pavlov V, Maslyankov S, . Multimodal approach for metastatic colorectal cancer – a clinical model: Case report. Int J Surg Med. 2019; 5(4): 218-222. doi:10.5455/ijsm.Metastatic-CRC-patients


Web Style

TP, KA, Pavlov V, Maslyankov S, . Multimodal approach for metastatic colorectal cancer – a clinical model: Case report. http://www.ejos.org/?mno=41467 [Access: February 23, 2020]. doi:10.5455/ijsm.Metastatic-CRC-patients


AMA (American Medical Association) Style

TP, KA, Pavlov V, Maslyankov S, . Multimodal approach for metastatic colorectal cancer – a clinical model: Case report. Int J Surg Med. 2019; 5(4): 218-222. doi:10.5455/ijsm.Metastatic-CRC-patients



Vancouver/ICMJE Style

TP, KA, Pavlov V, Maslyankov S, . Multimodal approach for metastatic colorectal cancer – a clinical model: Case report. Int J Surg Med. (2019), [cited February 23, 2020]; 5(4): 218-222. doi:10.5455/ijsm.Metastatic-CRC-patients



Harvard Style

, T. P. ., , K. A. ., Pavlov, V. . ., Maslyankov, S. & (2019) Multimodal approach for metastatic colorectal cancer – a clinical model: Case report. Int J Surg Med, 5 (4), 218-222. doi:10.5455/ijsm.Metastatic-CRC-patients



Turabian Style

, Tsvetelina Paycheva , Kostadin Angelov, Vasil Pavlov, Svilen Maslyankov, and . 2019. Multimodal approach for metastatic colorectal cancer – a clinical model: Case report. International Journal of Surgery and Medicine, 5 (4), 218-222. doi:10.5455/ijsm.Metastatic-CRC-patients



Chicago Style

, Tsvetelina Paycheva , Kostadin Angelov, Vasil Pavlov, Svilen Maslyankov, and . "Multimodal approach for metastatic colorectal cancer – a clinical model: Case report." International Journal of Surgery and Medicine 5 (2019), 218-222. doi:10.5455/ijsm.Metastatic-CRC-patients



MLA (The Modern Language Association) Style

, Tsvetelina Paycheva , Kostadin Angelov, Vasil Pavlov, Svilen Maslyankov, and . "Multimodal approach for metastatic colorectal cancer – a clinical model: Case report." International Journal of Surgery and Medicine 5.4 (2019), 218-222. Print. doi:10.5455/ijsm.Metastatic-CRC-patients



APA (American Psychological Association) Style

, T. P. ., , K. A. ., Pavlov, V. . ., Maslyankov, S. & (2019) Multimodal approach for metastatic colorectal cancer – a clinical model: Case report. International Journal of Surgery and Medicine, 5 (4), 218-222. doi:10.5455/ijsm.Metastatic-CRC-patients