E-ISSN 2367-699X | ISSN 2367-7414
 

Original Research 


Male Breast Cancer: No Evidence of Human Papillomavirus Etiology

Deniz Atasoy, Fatih Aydogan, Sevgi Ergin, Kenan Midilli, Sennur Ilvan, Cihan Uras, Ali Cengiz.

Abstract
Background and Aims
Once hypothetical, association between virus and cancer is a reality in many diseases. A possible role of Human papilloma virus (HPV) in breast carcinogenesis is conflicting.
The purpose of this study was to investigate the existence of HPV in archival breast cancer
specimens of male patients.
Material and Methods
The Pathology Department's archives between 1998-2008 were scanned. Tissue blocks of 27 male breast cancers and 27 gynecomastia tissue specimens were included to the study. DNA was extracted according to manufacturer's protocol.
Results
This study was not able to demonstrate HPV infection nor in male breast cancer or
gynecomastia tissue specimens.
Conclusions
This is the first study investigating the presence of HPV in male breast cancer samples.
All investigated tumoral and non-tumoral samples were negative for HPV DNA.
According to our findings, possibility of HPV function in in breast oncogenesis decreases.

Key words: Human papillomavirus; HPV; male; breast cancer; virus


 
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How to Cite this Article
Pubmed Style

Atasoy D, Aydogan F, Ergin S, Midilli K, Ilvan S, Uras C, Cengiz A, . Male Breast Cancer: No Evidence of Human Papillomavirus Etiology. doi:10.5455/ijsm.male-breast-cancer


Web Style

Atasoy D, Aydogan F, Ergin S, Midilli K, Ilvan S, Uras C, Cengiz A, . Male Breast Cancer: No Evidence of Human Papillomavirus Etiology. http://www.ejos.org/?mno=6322 [Access: January 18, 2019]. doi:10.5455/ijsm.male-breast-cancer


AMA (American Medical Association) Style

Atasoy D, Aydogan F, Ergin S, Midilli K, Ilvan S, Uras C, Cengiz A, . Male Breast Cancer: No Evidence of Human Papillomavirus Etiology. doi:10.5455/ijsm.male-breast-cancer



Vancouver/ICMJE Style

Atasoy D, Aydogan F, Ergin S, Midilli K, Ilvan S, Uras C, Cengiz A, . Male Breast Cancer: No Evidence of Human Papillomavirus Etiology. doi:10.5455/ijsm.male-breast-cancer



Harvard Style

Atasoy, D. ., Aydogan, F. ., Ergin, S. ., Midilli, K. ., Ilvan, S. ., Uras, C. ., Cengiz, A. . & (2019) Male Breast Cancer: No Evidence of Human Papillomavirus Etiology. doi:10.5455/ijsm.male-breast-cancer



Turabian Style

Atasoy, Deniz , Fatih Aydogan, Sevgi Ergin, Kenan Midilli, Sennur Ilvan, Cihan Uras, Ali Cengiz, and . 2019. Male Breast Cancer: No Evidence of Human Papillomavirus Etiology. doi:10.5455/ijsm.male-breast-cancer



Chicago Style

Atasoy, Deniz , Fatih Aydogan, Sevgi Ergin, Kenan Midilli, Sennur Ilvan, Cihan Uras, Ali Cengiz, and . "Male Breast Cancer: No Evidence of Human Papillomavirus Etiology." doi:10.5455/ijsm.male-breast-cancer



MLA (The Modern Language Association) Style

Atasoy, Deniz , Fatih Aydogan, Sevgi Ergin, Kenan Midilli, Sennur Ilvan, Cihan Uras, Ali Cengiz, and . "Male Breast Cancer: No Evidence of Human Papillomavirus Etiology." doi:10.5455/ijsm.male-breast-cancer



APA (American Psychological Association) Style

Atasoy, D. ., Aydogan, F. ., Ergin, S. ., Midilli, K. ., Ilvan, S. ., Uras, C. ., Cengiz, A. . & (2019) Male Breast Cancer: No Evidence of Human Papillomavirus Etiology. doi:10.5455/ijsm.male-breast-cancer