E-ISSN 2367-699X | ISSN 2367-7414
 

Original Research 


ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN

Zuvdija Cecunjanin, Amina Selimovi& 263;, Selma Miliši& 263;, Ermina Muji& 269;i& 263;.

Cited by (1)

Abstract
Objective: The purpose of our retrospective study was to investigate the necessity of some laboratory testing in patients with acute bronchiolitis before and after treatment.
Methods: We have taken blood samples of all children puncturing the cubital vein, and analyzed it using the Colter appliances-automatic counter blood count, for analyzes of a number of erythrocytes, leukocytes, platelets, differential blood count, Hct, Hb. CRP concentration in serum of patients determined by laser nephelometry with CardioPhase® high sensitivity C-reactive protein (hsCRP). For assessment of acid-base status and arterial blood gas analysis were used ABL5 and ABL700 Radiometer Copenhagen. We monitored the following parameters: pH, pCO2, HCO3-, total CO2, base excess, pO2, SpO2.
Results: There was a significant improvement of hypoxemia after management of acute bronchiolitis in the form of a significant increase in average values of pO2 and SpO2 after treatment of acute bronchiolitis. The average value of the number of leukocytes and value of CRP in children were significantly decreased before and after management of acute bronchiolitis. There was no significant difference in duration of hospitalization in term and preterm newborns.
Conclusion: No routine diagnostic tests are used routinely. However, there is an improvement of hypoxemia after management of acute bronchiolitis in children.

Key words: Bronchiolitis, Hematological Tests, Acid-Base Status, Blood Gas Analysis


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Zuvdija Cecunjanin
Articles by Amina Selimovi& 263;
Articles by Selma Miliši& 263;
Articles by Ermina Muji& 269;i& 263;
on Google
on Google Scholar
Article Statistics
 Viewed: 2085
Downloaded: 453
Cited: 1

REFERENCES
1. Scottish Intercollegiate Guidelines Network (SIGN). Bronhiolitis in children. A national clinical guideline. 2006. pp. 5-19.
2. American academy of Paediatrics Subcommittee on Diagnosis and Managment Of Bronhiolitis. Diagnosis and managment of bronhiolitis. Paediatrics 2006;118:1774-93. Zorc JJ, Hall CB: Bronchiolitis: recent evidence on diagnosis and management. Paediatrics 2010, 125:342-349. [DOI via Crossref]    [Pubmed]   
3. Nagakumar P, Doull I: Current therapy for bronchiolitis. Arch Dis Child 2012, 97:827-830. [DOI via Crossref]    [Pubmed]   
4. Wainwright C: Acute viral bronchiolitis in children- a very common condition with few therapeutic options. Paediatr Respir Rev 2010, 11:39-45. [DOI via Crossref]    [Pubmed]   
5. Bordley WC, Viswanathan M, King VJ, Sutton SF, Jackman AM, Sterling L, Lohr KN: Diagnosis and testing in bronchiolitis: a systematic review. Arch Pediatr Adolesc Med 2004, 158:119-126. [DOI via Crossref]    [Pubmed]   
6. Johnson LW, Robles J, Hudgins A, Osburn S, Martin D, Thompson A: Management of bronchiolitis in the emergency department: impact of evidence-based guidelines? Paediatrics 2013, 131(Suppl 1):S103-S109. [DOI via Crossref]    [Pubmed]   
7. Ferronato AE, Gilio AE, Ferraro AA, Paulis M, Vieira SE: Etiological diagnosis reduces the use of antibiotics in infants with bronchiolitis. Clinics (Sao Paulo) 2012, 67:1001-1006. [DOI via Crossref]   
8. Pappas R, Pardue J, Quinonez R, Fine BR, Ryan M: Decreasing unnecessary utilization in acute bronchiolitis care: results from the value in inpatient paediatrics network. J Hosp Med 2013, 8:25-30. [DOI via Crossref]    [Pubmed]   
9. Parikh K, Hall M, Teach SJ: Bronchiolitis Management Before and After the AAP Guidelines. Paediatrics 2014, 133:e1-7. [DOI via Crossref]    [Pubmed]   
10. Øymar K, Skjerven H, Mikalsen BI. Acute bronciolitis in infants, a review. Scand J Trauma Resusc Emerg Med, 2014:22-23
11. Purcell K, Fergie J. Lack of usefulness of an abnormal white blood cell count for predicting a concurrent serious bacterial infection in infants and young children hospitalized with respiratory syncytial virus lower respiratory tract infection. Pediatr Infect Dis J. 2007; 26:311-15. [DOI via Crossref]    [Pubmed]   
12. Edo Hasanbegović, Amra Džinović, Sniježana Hasanbegović, Epidemiological and clinical features of bornchiolitis in childhood. Medicinski žurnal 2009;15 (3): 95-98
13. Iqbal S. M. J.,Afzal M. F.,Sultan M. A. Acute Bronchiolitis: Epidemiological and Clinical Study. Annals. 2009;15(4):203-205
14. Chi-Chun Sung, Hsin Chi, Nan-Chang Chiu, Daniel Tsung-Ning Huang, Li-Chuan Weng, Nai-Yu Wang, Fu-Yuan Huang. Viral etiology of acute lower respiratory tract infections in hospitalized young children in Northern Taiwan. Journal of Microbiology, Immunology and Infection 2011;44:184 -190 [DOI via Crossref]    [Pubmed]   
15. Alverson B1, McCulloh RJ, Dawson-Hahn E, Smitherman SE, Koehn KL. The clinical management of preterm infants with bronchiolitis. Hosp Pediatr. 2013 Jul;3(3):244-50. [DOI via Crossref]    [Pubmed]   
16. Gholamreza Soleimani, Elham Shafighi Shahri, Somayeh Rashidi, Zahra Salari, Alireza Ansari Moghadam. Epidemiology, Clinical, and Laboratory Characteristics of Bronchiolitis in Hospitalized Children. J Compr Ped. 2014; 5(3): e18808 [DOI via Crossref]   
17. Savić N, et al. Clinical characteristics of respiratory syncytial virus infection in neonates and young infants. Vojnosanit Pregl 2011; 68(3): 220–224. [DOI via Crossref]   
18. Muhi K. Acute bronchiolitis. Inter Public Manag J, 2002;2:77-82.
19. Hakam K, Bajraktarević A, SporiÅ¡ević L. RSV infekcija kod novorođenčadi i dojenčadi sa posebnim osvrtom na modernu prevenciju i terapiju. Glasilo podružnice Srpskog lekarskog druÅ¡tva Zaječar 2005; 30 (1): 33-36
20. Saijo M, Ishii T, Kokubo M, Murono K, Takimoto M, Fujita K. White blood cell count, C-reactive protein and erythrocyte sedimentation rate in respiratory syncytial virus infection of the lower respiratory tract. Acta Paediatr Jpn 1996;38(6):596-600. [DOI via Crossref]    [Pubmed]   
21. Prat C, Dominguez J, Rodrigo C, Gimenez M, Azuara M, Jimenez O, et al. Procalcitonin, C-reactive protein and leukocyte count in children with lower respiratory tract infection. Pediatr Infect Dis J 2003;22(11):963-7. [DOI via Crossref]    [Pubmed]   
22. Martinez-Baylach J, Retana Castan A, Cubells Riero J. Clinical and epidemiological study of acute bronchiolitis in patients less than one year of age. Acta Pediatr Esp 2004;62(7):275-280.
23. Mulholland EK, Olinsky A, Shann FA. Clinical findings and severity of acute bronchiolitis. Lancet 1990;335(8700):1259-61. [DOI via Crossref]   
24. Maneker AJ, Petrack EM, Krug SE. Contribution of routine pulse oximetry to evaluation and management of patients with respiratory illness in a paediatric emergency department. Ann Emerg Med 1995;25(1):36-40. [DOI via Crossref]   
25. Mallory MD, Shay DK, Garrett J, Bordley WC. Bronchiolitis management preferences and the influence of pulse oximetry and respiratory rate on the decision to admit. Paediatrics 2003;111(1):e45-51. [DOI via Crossref]   
26. Wang EE, Law BJ, Stephens D. Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC) prospective study of risk factors and outcomes in patients hospitalized with respiratory syncytial viral lower respiratory tract infection. J Pediatr 1995;126(2):212-9. [DOI via Crossref]   

This Article Cited By the following articles

The effect of delivery type on neonatal blood indices in an Iranian population
Biomedical Research and Therapy 2018; 5(10): 2768-2775.

1
 
How to Cite this Article
Pubmed Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #;. ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN. Int J Surg Med. 2016; 2(3): 171-175. doi:10.5455/ijsm.acute-bronchiolitis


Web Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #;. ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN. http://www.ejos.org/?mno=222578 [Access: March 24, 2019]. doi:10.5455/ijsm.acute-bronchiolitis


AMA (American Medical Association) Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #;. ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN. Int J Surg Med. 2016; 2(3): 171-175. doi:10.5455/ijsm.acute-bronchiolitis



Vancouver/ICMJE Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #;. ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN. Int J Surg Med. (2016), [cited March 24, 2019]; 2(3): 171-175. doi:10.5455/ijsm.acute-bronchiolitis



Harvard Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #; (2016) ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN. Int J Surg Med, 2 (3), 171-175. doi:10.5455/ijsm.acute-bronchiolitis



Turabian Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #;. 2016. ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN. International Journal of Surgery and Medicine, 2 (3), 171-175. doi:10.5455/ijsm.acute-bronchiolitis



Chicago Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #;. "ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN." International Journal of Surgery and Medicine 2 (2016), 171-175. doi:10.5455/ijsm.acute-bronchiolitis



MLA (The Modern Language Association) Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #;. "ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN." International Journal of Surgery and Medicine 2.3 (2016), 171-175. Print. doi:10.5455/ijsm.acute-bronchiolitis



APA (American Psychological Association) Style

Zuvdija Cecunjanin, Amina Selimovi and #;, Selma Miliši and #;, Ermina Muji and #;i and #; (2016) ASSESSMENT OF HEMATOLOGICAL PARAMETERS, ACID-BASE STATUS AND ARTERIAL BLOOD GAS TEST BEFORE AND AFTER TREATMENT OF ACUTE BRONCHIOLITIS IN CHILDREN. International Journal of Surgery and Medicine, 2 (3), 171-175. doi:10.5455/ijsm.acute-bronchiolitis