E-ISSN 2367-699X | ISSN 2367-7414
 

Case Report 


MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar.

Abstract
Extramedullary plasmocytoma is an expansion of a single clone of immunoglobulin-secreting plasma cells without evidence of multiple myeloma. It is un uncommon entity that occurs usually in head and neck area. It is radiocurable at average doses while adjuvant chemotherapy is still controversial. Progression rates to multiple myeloma are lower than bone plasmacytoma. We report three cases of extramedullary plasmacytoma and through a literature review we discuss radiation modalities as well as evolutionary aspects.

Key words: extramedullary plasmacytoma, radiation therapy, prognosis


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Naoual Benhmidou
Articles by Fadoua Rais
Articles by Khadija Bellahammou
Articles by Abdelhak Maghous
Articles by Hasna Loughlimi
Articles by Meryem kamouni
Articles by Fadila Kouhen
Articles by Sanaa Elmajjaoui
Articles by Tayeb Kebdani
Articles by Hanan Elkacemi
Articles by Noureddine Benjaafar
on Google
on Google Scholar
Article Statistics
 Viewed: 1261
Downloaded: 375
Cited: 0

REFERENCES
1 Cotran RS. Robbins Pathologic Basis of Diseases. Robbins SL and Kumar V, eds. 5th ed., W.B. Saunders Company, 1994. [Pubmed]   
2 British Committee for Standards in Hematology. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. British Journal of Hematology 2004 ;( 124):717-726
3 Shimaoka K, Gailani S, Tsukada Y, Barcos M. Plasma cell neoplasm involving the thyroid. Cancer 1978; 41(3): 1140-1146. [DOI via Crossref]   
4 Aozasa K, Inoue A, Yoshimura H, Miyauchi A, Matsuzuka F, Kuma K. Plasmacytoma of the thyroid gland. Cancer 1986; 58(1): 105-110. [DOI via Crossref]   
5 Ozsahin M., Tsang R.W. et al. Outcomes and Patterns of failure in solitary plasmacytoma: a multicenter rare cancer network study of 258 patients. International Journal of Radiation Oncology 2006; (64): 210-217
6 Durie BG, Kyle RA, Belch A, et al. Myeloma management guidelines: a consensus report from the scientific advisors of the International Myeloma Foundation. Hematol J 2003; (4): 379-398. [DOI via Crossref]    [Pubmed]   
7 Wilder RB, Ha CS, Cox JD, et al. Persistence of myeloma protein for more than one year after radiotherapy is an adverse prognostic factor in solitary plasmacytoma of bone. Cancer 2002; (94):1532-1537. [DOI via Crossref]    [Pubmed]   
8 David Knobel, Abderrahim Zouhair, Richard W Tsang, Philip Poortmans, Yazid Belkacémi, Michel Bolla, Fazilet Dinçbas Oner, Christine Landmann, Bernard Castelain, Mahmut Ozsahin. Prognostic factors in solitary plasmacytoma of the bone: a multicenter Rare Cancer Network study. BMC Cancer 2006: 6-118.
9 Sasaki R1, Yasuda K, Abe E, Uchida N, Kawashima M, Uno T, Fujiwara M, Shioyama Y, Kagami Y, Shibamoto Y, Nakata K, Takada Y, Kawabe T, Uehara K, Nibu K, Yamada S. Multi-institutional analysis of solitary extramedullary plasmacytoma of the head and neck treated with curative radiotherapy. Int J Radiat Oncol Biol Phys. 2012; (2):626-34. [Pubmed]   
10 Galieni P, Cavo M, Pulsoni A, et al. Clinical outcome of extramedullary plasmacytoma. Haematologica 2000; (85): 47-51. [Pubmed]   
11 M. Hughes, R. Soutar, H. Lucraft, R. Owen, J. Bird. Guidelines on the diagnosis and management of solitary plasmacytoma of bone, extramedullary plasmacytoma and multiple solitary plasmacytomas: 2009 update
12 Mendenhal W, Mendenhal C, Mendenhal N. Solitary plasmocytoma of bone and soft tissues. Am J Otolaryngol 2003; (24): 395-9. [DOI via Crossref]   
13 Sautar R. Guidelines on the diagnosis and management of solitary plasmocytoma of bone and solitary extramedullary plasmocytoma. BJH 2004;124:717-26. [DOI via Crossref]   
14 Mayr NA, Wen BC, Hussey DH, et al. The role of radiation therapy in the treatment of solitary plasmacytomas. Radiother Oncol 1990;17:293–303.
15 Harwood AR, Knowling MA, Bergsagel DE. Radiotherapy of extramedullary plasmacytoma of the head and neck. Clin Radiol 1981; (32): 31-36. [DOI via Crossref]   
16 Knowling MA, Harwood AR, Bergsagel DE. Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumors of bone. J Clin Oncol 1983; (1): 255-262. [Pubmed]   
17 Tsang RW, Gospodarowicz MK, Pintilie M, et al. Solitary plasmacytoma treated with radiotherapy: impact of tumor size on outcome. Int J Radiat Oncol Biol Phys 2001; (50): 113-120. [DOI via Crossref]   
18 Tournier-Rangeard L, Lapeyre M, Graff-Caillaud P, Mege A, Dolivet G, Toussaint B, Charra-Brunaud C, Hoffstetter S, Marchal C, Peiffert D. Radiotherapy for solitary extramedullary plasmacytoma in the head-and-neck region: A dose greater than 45 Gy to the target volume improves the local control. Int J Radiat Oncol Biol Phys. 2006; 64(4):1013-1017. [DOI via Crossref]    [Pubmed]   
19 MendenhallCM, TharTL, Million RR. Solitaryplasmacytoma of bone and soft tissue. Int J Radiat Oncol Biol Phys 1980; (6): 1497-1501 [DOI via Crossref]   
20 HollandJ,TrenknerDA,WassermanTH,etal.Plasmacytoma: Treatment results and conversion to myeloma. Cancer 1992; (69): 1513-1517. [DOI via Crossref]   
21 Aviles A, Huerta-Guzman J, Delgado S, et al. Improved outcome in solitary bone plasmacytomata with combined therapy. Hematol Oncol 1996; (14):111-117. [DOI via Crossref]   
22 Chang MY, Shih LY, Dunn P, et al. Solitary plasmacytoma of bone. J Formos Med Assoc 1994; (93): 397-402 [Pubmed]   
23 BacharG,GoldsteinD,BrownD,et al.Solitary extramedullary plasmacytoma of the head and neck long-term outcome analysis of 68 cases. Head Neck 2008; (30):1012-1019. [DOI via Crossref]    [Pubmed]   

How to Cite this Article
Pubmed Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar. MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK. Int J Surg Med. 2016; 2(3): 183-186. doi:10.5455/ijsm.extramedullary-plasmocytoma


Web Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar. MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK. http://www.ejos.org/?mno=226161 [Access: January 18, 2019]. doi:10.5455/ijsm.extramedullary-plasmocytoma


AMA (American Medical Association) Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar. MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK. Int J Surg Med. 2016; 2(3): 183-186. doi:10.5455/ijsm.extramedullary-plasmocytoma



Vancouver/ICMJE Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar. MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK. Int J Surg Med. (2016), [cited January 18, 2019]; 2(3): 183-186. doi:10.5455/ijsm.extramedullary-plasmocytoma



Harvard Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar (2016) MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK. Int J Surg Med, 2 (3), 183-186. doi:10.5455/ijsm.extramedullary-plasmocytoma



Turabian Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar. 2016. MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK. International Journal of Surgery and Medicine, 2 (3), 183-186. doi:10.5455/ijsm.extramedullary-plasmocytoma



Chicago Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar. "MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK." International Journal of Surgery and Medicine 2 (2016), 183-186. doi:10.5455/ijsm.extramedullary-plasmocytoma



MLA (The Modern Language Association) Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar. "MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK." International Journal of Surgery and Medicine 2.3 (2016), 183-186. Print. doi:10.5455/ijsm.extramedullary-plasmocytoma



APA (American Psychological Association) Style

Naoual Benhmidou, Fadoua Rais, Khadija Bellahammou, Abdelhak Maghous, Hasna Loughlimi, Meryem kamouni, Fadila Kouhen, Sanaa Elmajjaoui, Tayeb Kebdani, Hanan Elkacemi, Noureddine Benjaafar (2016) MANAGEMENT OF EXTRAMEDULLARY PLASMOCYTOMA OF HEAD AND NECK. International Journal of Surgery and Medicine, 2 (3), 183-186. doi:10.5455/ijsm.extramedullary-plasmocytoma